Police said that the accident happened around 4.30 am in the area falling under Etmadpur police station area. The Uttar Pradesh Roadways bus was coming from Kanpur and was going towards Agra bus stand.
Police sub-inspector Udayveer Singh said that the bus first hit the canter standing on the road and then climbed the divider.
The deceased have been identified as Mani (60), Resham (65), Mandleshwar (28) and Narendra Singh Chauhan (52), he said.
According to SI Singh, the injured are undergoing treatment at Sarojini Naidu Medical College here.